Fundamentals of Biochemistry

Introduction to Chemical Bonds, pH, Buffers, Carbohydrates, Lipids, Proteins.

Introduction to Metabolism-Glycolysis-Citric acid cycle Gluconeogenesis- Glycogen metabolism- Glycogenesis Glycogenolysis- Biochemical aspects of Diabetes Mellitus.

Introduction-Metabolism of amino acids-Transamination Deamination-Metabolism of ammonia-Urea cycle-Biosynthesis of amino acids-Disorders of tyrosine (phenylalanine) metabolism.

Introduction Fatty acid oxidation-Ketone bodies & Ketogenesis- Biosynthesis of Fatty acids-Eicosanoids- Cholesterol Biosynthesis- Lipoproteins-Disorders of Lipid metabolism-Nucleic acids: Biosynthesis of Purine and Pyrimidines-Degradation of purine nucleotides and pyrimidine nucleotides-Disorders of Purine and pyrimidine metabolism.

Introduction-Bioenergetics, High energy compounds, Biological oxidation-Electron transport chain, Oxidative phosphorylation, Chemiosmotic theory - Shuttle pathways – Glycerol phosphate Shuttle, Malate aspartate Shuttle –Shunt pathways.