BBI502

Fundamentals of Omics

L-T-P3-1-0 Credits4 Session2026-27 TypeTheory
Appears in 1 semester

B.Tech Bioinformatics · Sem 5 (Core)

Syllabus

5 units · 40 lecture hours
Unit1

Unit 1: INTRODUCTION TO OMICS

8 hrs

Overview of genomics, transcriptomics, and proteomics; role of AI in biological data analysis and Omics.

Unit2

Unit 2: GENOMICS

8 hrs

Genome sequencing, gene prediction, variant calling; AI tools for genome annotation (DeepVariant, AUGUSTUS, GENSCAN).

Unit3

Unit 3: TRANSCRIPTOMICS

8 hrs

RNA-Seq data analysis, expression profiling, clustering and classification differential gene expression prediction. Role of AI in Transcriptomics.

Unit4

Unit 4: PROTEOMICS

8 hrs

Protein identification, quantitation, and structure prediction. Role of AI in Proteomics.

Unit5

Unit 5: MULTIOMICS DATA INTEGRATION

8 hrs

Multiomics – Combination of data from genomics, proteomics, transcriptomics and metabolomics, AI in healthcare, diagnostics and personalized medicine.

Course Outcomes (COs)5 outcomes

After completion of the course student will be able to:

  1. CO1Explain foundational Omics concepts and the role of AI in biological data analysis.K2
  2. CO2Apply AI tools for gene annotation of genome-sequencing data.K3
  3. CO3Implement RNA-Seq pipelines and predict differential gene expression using AI.K3
  4. CO4Explain protein identification methods and AI models for structure prediction.K2
  5. CO5Apply AI-based integration of multiomics datasets for personalized healthcare solutions.K3

TEXT BOOKS

  1. / REFERENCES
  2. Andreas Baxevanis & B.F. Ouellette, Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, Wiley.
  3. S.C. Rastogi et al., Bioinformatics: Methods and Applications, Springer.
  4. Stuart Russell & Peter Norvig, Artificial Intelligence: A Modern Approach, Prentice Hall.
  5. David Mount, Bioinformatics: Sequence and Genome Analysis, Cold Spring Harbor Laboratory Press.
  6. S.C. Rastogi, Namita Mendiratta, Parag Rastogi, Bioinformatics: Methods and Applications – Genomics, Proteomics and Drug Discovery. Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh
  7. Singh, Bioinformatics: Genomics and Proteomics.
  8. Devarajan Thangadurai, Jeyabalan Sangeetha, Genomics and Proteomics. Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh

Official AKTU syllabus

This subject is on page 7, 8, 9 of the original AKTU PDF.

Official AKTU syllabus PDF ↗