UNIQUE SERIES AKTU Syllabus
BP405T

Systemic Pharmacology I (Theory)

L-T-P3-0-0 Credits3 Session2026-27 TypeTheory
Appears in 1 semester

B.Pharm · Sem 4 (Core)

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Syllabus

5 units · 45 lecture hours
Unit1

Unit 1

10 hrs

Pharmacology of drugs acting on the peripheral nervous system a) Organization and functions of PNS. b) Neurohumoral transmission, co-transmission. Neurotransmitters and their receptors, including non-adrenergic and non-cholinergic (NANC) neurotransmitters. c) Parasympathomimetic and Parasympatholytic drugs. d) Sympathomimetic and sympatholytic drugs. e) Skeletal muscle relaxants (peripheral and central). f) Drugs used in the treatment of myasthenia gravis and glaucoma

Unit2

Unit 2

10 hrs

Pharmacology of drugs acting on the cardiovascular system a) Introduction to cardiovascular hemodynamic and cardiac electrophysiology. b) Drugs used in congestive cardiac failure. c) Anti-arrhythmic drugs. d) Anti-anginal and newer anti-ischemic drugs. e) Anti-hypertensive drugs. f) Shock, types of shocks and drugs used in their management. g) Stroke, types of strokes and drugs used in their management

Unit3

Unit 3: Pharmacology of drugs acting on blood and kidney

10 hrs
  • Pharmacology of drugs acting on blood a) Anti-platelet agents b) Coagulants and anticoagulants. c) Fibrinolytics and Plasma expanders. d) Haematinics. e) Anti-hyperlipidaemic drugs.
  • Pharmacology of drugs acting on kidney a) Diuretics. b) Anti-diuretics.
Unit4

Unit 4

9 hrs

Pharmacology of autacoids and related drugs a) Introduction to autacoids and their classification. Therapeutic significance of important agonists and antagonists of prostaglandins, thromboxane, leukotrienes, angiotensin, bradykinin and substance P. b) Histamine and antihistamines. c) 5-HT, its agonists and antagonists, drugs used in migraine. d) Non-steroidal anti-inflammatory drugs, antipyretics and analgesics. e) Anti-gout and Antirheumatic drugs including Disease Modifying Antirheumatic Drugs (DMARDs).

Unit5

Unit 5

6 hrs

i) Pharmacology of Drugs acting on respiratory system a) Drugs used in the treatment of bronchial asthma and COPD. b) Definitions, classification and therapeutic uses of nasal decongestants, mucolytics, expectorants and antitussives. c) Respiratory stimulants. ii) Pharmacology of Drugs acting on immune system Mechanism of action, adverse effects and therapeutic uses of important classes of immune stimulants and immunosuppressants.

Course Objectives6 points
  • The objectives of this course are to:
  • Develop a comprehensive understanding of neurohumoral transmission, neurotransmitters, and the organization and function of the autonomic nervous system.
  • Provide knowledge of the classification, mechanisms of action, and pharmacological effects of various classes of drugs.
  • Explain the pharmacology of drugs acting on the peripheral nervous system, cardiovascular system, and urinary system.
  • Describe the physiological roles of autacoids and the pharmacology of drugs used in the management of pulmonary diseases and related disorders.
  • Familiarize students with the pharmacology of drugs acting on the immune system, hematopoietic system, and blood, and relate pharmacological principles to clinical conditions through case-based learning.
Course Outcomes (COs)5 outcomes

After completion of the course student will be able to:

  1. CO1Explain the classification of neurotransmitters and describe neurohumoral transmission, including the organization, function, and pharmacological modulation of the autonomic nervous system.
  2. CO2Classify and explain the mechanisms of action, pharmacological effects, and therapeutic uses of drugs used in cardiovascular disorders such as heart failure, arrhythmias, hypertension, angina, and lipid disorders.
  3. CO3Describe the pharmacology and therapeutic uses of drugs acting on blood and kidney, including anticoagulants, antiplatelet agents, hematinics, and diuretics.
  4. CO4Explain the physiological roles of autacoids and analyze the pharmacology of drugs that modulate autacoid pathways, including antihistamines, antimigraine agents, NSAIDs, and antirheumatic drugs.
  5. CO5Evaluate the mechanisms of action, therapeutic uses, and adverse effects of drugs acting on the respiratory and immune systems.
Recommended References (Preferably latest editions):6 books
  1. Brunton, L., Hilal-Dandan, R. and Knollmann, B. Pharmacological Basis of Therapeutics. McGraw-Hill Education.
  2. Craig, C. R. and Stitzel, R. E. Modern Pharmacology with Clinical Applications. Lippincott Williams & Wilkins.
  3. DiPiro, J. T., Talbert, R. L., Yee, G. C. and Matzke, G. R. Pharmacotherapy: A Pathophysiologic Approach. McGraw-Hill Education.
  4. Katzung, B. G. and Trevor, A. J. Basic and Clinical Pharmacology. McGraw-Hill Education.
  5. Rang, H. P., Dale, M. M., Ritter, J. M., Flower, R. J. and Henderson, G. Rang and Elsevier.
  6. Tripathi, K. D. Essentials of Medical Pharmacology. Jaypee Brothers Medical Publishers. Course Title Course Type

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Official AKTU syllabus

This subject is on page 106, 107, 108, 109 of the original AKTU PDF.

Official AKTU syllabus PDF ↗