Medicinal Chemistry (Practical)

• The objectives of this course are to:
• Comprehend the fundamental principles of drug synthesis, assay, and monograph analysis.
• Acquire practical skills in the synthesis of selected drug molecules and intermediates.
• Develop proficiency in performing qualitative and quantitative assays of drugs.
• Understand the requirements and procedures involved in drug monograph analysis.
• Apply appropriate techniques and methodologies for the preparation, assay, and monograph analysis of various drugs.

After completion of the course student will be able to:

1. CO1Demonstrate the ability to synthesize various drug molecules and intermediates using standard laboratory procedures.
2. CO2Perform qualitative and quantitative assays of drugs with accuracy and precision.
3. CO3Analyze and interpret drug monographs according to pharmacopeial standards.
4. CO4Utilize appropriate instrumentation and techniques for drug preparation, assay, and monograph analysis.
5. CO5Document and report experimental procedures and results in a clear and concise manner.

1. Abraham, D. J. and Rotella, D. P. Development. John Wiley & Sons.
2. Beckett, A. H. and Stenlake, J. B. Practical Pharmaceutical Chemistry. CBS Publishers & Distributors.
3. Furniss, B. S., Hannaford, A. J., Smith, P. W. G. and Tatchell, A. R. of Practical Organic Chemistry. Pearson Education.
4. Indian Pharmacopoeia Commission. Indian Pharmacopoeia. Indian Pharmacopoeia Commission.
5. Kar, A. Advanced Practical Medicinal Chemistry. New Age International Publishers.
6. Lednicer, D. The Organic Chemistry of Drug Synthesis. John Wiley & Sons.
7. Moffat, A. C., Osselton, M. D. and Widdop, B. Pharmaceutical Press.
8. United States Pharmacopeial Convention. United States Pharmacopeia National Formulary (USP NF). United States Pharmacopeial Convention.
9. Vogel, A. I. Longman Scientific & Technical. Course Title Course Type