Systemic Pharmacology II (Theory)

Pharmacology of Drugs Acting on Central Nervous System Neurohumoral transmission in the CNS; physiological roles of GABA, glutamate, glycine, serotonin, and dopamine. a. General anesthetics, pre-anaesthetic medications, and local anaesthetic agents b. Sedative hypnotics c. Alcohol and disulfiram d. Opioids, opiate analgesics, and antagonists e. Drugs used in epilepsy

Pharmacology of Drugs Used in Psychiatry a. Antipsychotics, antidepressants, anti-anxiety drugs, mood stabilizers, CNS stimulants, and hallucinogens b. Substance abuse, drug addiction, and general principles of de-addiction

Chemotherapy i) Introduction a. Definitions of chemotherapy, chemotherapeutic index, antibiotics, and antimicrobial agents b. Concept of selective targeting in chemotherapy c. Classification of antimicrobial agents based on mechanism of action d. Concept of superinfection, chemoprophylaxis, and combined use of antibiotics e. Antimicrobial resistance: causes, mechanisms, and preventive measures ii) Antimicrobial Agents Classification, mechanism of action, adverse drug reactions, and therapeutic uses of: Sulphonamides and cotrimoxazole Fluoroquinolones Penicillins and cephalosporins Macrolides and tetracyclines Linezolid Carbapenems and monobactams Chloramphenicol and aminoglycosides iii) Chemotherapy of Diseases Drugs used in the treatment of: Fungal infections Viral infections Helminthiasis Urinary tract infections Tuberculosis Leprosy Malaria Amoebiasis Neoplastic diseases

Pharmacology of Drugs Acting on Endocrine System a. Introduction to basic concepts of endocrinology b. Thyroid and antithyroid agents c. Parathormone, calcitonin, and vitamin D d. Insulin and oral hypoglycaemic agents e. ACTH and corticosteroids f. Oral contraceptives g. Drugs acting on the uterus h. PCOD

Drugs Acting on Gastrointestinal Tract a. Drugs used in peptic ulcer b. Drugs used for constipation and diarrhoea c. Emetics and anti-emetics d. Digestants, carminatives, appetizers, and anorectics definitions and examples