Systemic Pharmacology II (Practical)

List of Experiments / Activities

1. SYSTEMIC PHARMACOLOGY II (Practical) Core Credit Hours Per Week (L-T-P) Max. Hours. L T P
2. 2-- --
3. 60Maximum Marks SE ESE
4. (Minimum 12 experiments must be performed)
5. 1Evaluation of analgesic activity of centrally and peripherally acting analgesics using Eddie's hot plate, tail-flick, tail immersion, and acetic acid-induced writhing methods through interactive computer simulation.
6. 2Evaluation of antiepileptic activity using maximal electroconvulsive shock (MES)- induced seizures through interactive computer simulation.
7. 3Demonstration of the antiepileptic activity using pentylenetetrazol-induced seizures through interactive computer simulation.
8. 4Evaluation of antidepressant activity of drugs using the tail suspension test through interactive computer simulation.
9. 5Demonstration and study of locomotor activity using actophotometer through interactive computer simulation.
10. 6Evaluation of antianxiety activity using the elevated plus maze or zero maze model through interactive computer simulation.
11. 7Evaluation of antipsychotic activity of drugs using inhibition of conditioned response on Cook's pole climbing apparatus through interactive computer simulation.
12. 8Study of the effect of drugs on learning and memory using the Morris water maze test through interactive computer simulation.
13. 9Study of antiulcer activity using indomethacin-induced or pylorus ligation-induced ulcer models.
14. 10Estimation of the concentration of oxytocin on isolated rat uterus preparation using a suitable method through interactive computer-based simulation.
15. 11Estimation of drug concentration by 3-point or 4-point bioassay through interactive computer simulation.
16. 12Bioassay of histamine using matching, bracketing, or interpolation methods on suitable isolated tissue preparation with the help of interactive computer simulation.
17. 13Study of cell culture techniques, including types of cell culture, laboratory instruments/equipment, culture media, and growth of cell cultures in laboratory facilities.
18. 14Study of antibacterial sensitivity testing of urine culture using techniques such as the disc diffusion method (theoretical details/case studies).
19. 15Demonstration using databases and software packages for predicting drug activity, ADME properties, and toxicity.
20. 16Study of electrophoresis of protein and DNA samples and gel visualization techniques.
21. 17Construction of pharmacological networks using predicted drug targets and disease genes with activity prediction databases, disease gene databases, and suitable software.